Endocrine Abstracts

Background and aims: Diabetic osteopathy in patients with type 1 diabetes (T1DM) is obvious. However, approaches to its diagnosis are still ambiguous. Thus, the aim was to study the features of serum osteo-specific parameters and dual energy X–ray absorptiometry (DXA) data in T1DM patients.Materials and methods: 157 patients with T1DM (105 women, 52 males) (mean age: 32.5 (25.5–41.6) yrs, duration of DM: 13 (7–20) yrs, age of manifestation...

Aim: To evaluate bone mineral density (BMD) and its relationship with calcium (Ca) and phosphorus (P) metabolism in children with obesity.Methods: We examined 105 children in the University Hospital (Minsk) from 2011 to 2015 yrs. Their anthropometric parameters (height, weight, BMI) were determined. Body composition with evaluating of mineral component were made by dual energy X-ray absorptiometry with the calculation of feet, hands, spine, ribs, hips BM...

Currently relationship between the decrease in vitamin D (VD) levels and the formation of bone pathology has established. The presence of certain VD receptor (VDR) polymorphisms has been suggested to be associated with the serum VD. Therefore, the aim of study was to assess the association between VDR single nucleotide polymorphisms (SNPs) in type 1 diabetic patients and serum VD.Materials and methods: We studied 66 type 1 diabetic (T1D) patients (28 men...

Objective: To study the effect of parathyroidectomy (PTE) on the BMD in postmenopausal women with primary hyperparathyroidism (PHPT).Materials and methods: We studied 38 postmenopausal women with mild PHPT without osteoporosis (T-score ≥ −2,5 by DXA). In 20 patients was performed PTE, the comparison group:18 postmenopausal patients with PHPT. The duration of observation was 1 year. Examination: total calcium, Ca++, phosphorus, PTH,...

Background and aim: Hypersomatotropism is known to be associated with musculoskeletal disorders, particularly, osteoporosis and increased fracture rates. However controversial data about the effects of acromegaly on bone mineral density (BMD) have been published. The aim of our research was to evaluate bone mineral density (BMD) in patients with hypersomatotropism.Materials and methods: The study included 66 patients (20 men, 44 women) with hypersomatotr...